Updated On: August 20, 2024
Passionflower is a natural remedy used as a sleep aid for insomnia and a way to calm anxiety symptoms in some people. This perennial climbing vine is native to southeastern parts of the United States and Central and South America. It’s been used as an herbal medicine for centuries due to its healing properties for everything from wounds to earaches to its calming effect on the nervous system.
While more studies are needed, but some research suggests that passionflower might indeed have a positive impact on anxiety symptoms for some people.
Reader’s note: Be sure to talk to your therapist, psychiatrist, and/or doctor before you start passionflower (especially if you have mental health concerns). While passionflower can be an over-the-counter supplement, there may be serious side effects that can affect your mental health in unexpected ways.
Research has shown promise that passionflower has positive effects on anxiety symptoms, but further investigation is needed to fully understand the efficacy and potential — and safety — of passionflower for anxiety
Anxiety relieving effects of passionflower are thought to be due to a group of compounds called flavonoids. Some research shows these compounds can bind with specific receptors in the brain, leading to increased levels of gamma-aminobutyric acid (GABA). GABA is a neurotransmitter in the brain linked to relaxation and mood regulation.
Multiple studies have examined the potential benefits of passionflower in treating anxiety. One study found that people who took an extract containing herbs, including passionflower, significantly reduced generalized anxiety disorder (GAD) symptoms. The study concluded that a large-scale trial was justified.
Another study that was a double-blind, randomized controlled trial found that people undergoing surgery experienced less preoperative anxiety when they were given oral doses of passionflower compared to those who received the placebo. In fact, the group that received passionflower had numerical rating scale (NRS) anxiety scores that were “significantly lower” than the placebo group.These and other studies suggest that passionflower anxiety relief might be a good option for some people. That said, more research is needed before we can truly understand the potential effectiveness and optimal dosing when using passionflower for anxiety
Get support for anxiety fast and reach a calmer mindset. Therapy for anxiety is covered by most insurance plans.
Like any medication or drug — even over-the-counter (OTC) or herbal remedies — it’s essential to be aware of possible side effects and interactions. You should always consult your doctor or mental healthcare provider before you start any treatment with passionflower for anxiety. Even supplements and herbs can cause various reactions, so knowing the following is critical.
Passionflower might be dangerous for the following people:
Passionflower might cause drug interactions and adverse reactions. For example:
Expert Insight
“There is a need for more studies and research regarding the efficacy of passionflower for mental health issues. You should always consult with your doctor before starting anything, including herbal supplements and teas for health reasons. There can be certain side effects you may not be aware of so it is better to get more information about it first.”Licensed Mental Health Counselor (LMHC), MA, MSc Bisma Anwar
If you’re thinking about using Passionflower for anxiety, make sure you understand the different ways you can consume it. Popular ways to take Passionflower include:
If you’re looking for natural ways to relieve anxiety, explore passionflower and other supplements, herbs, and remedies to find the best treatment for your symptoms. Many other herbal supplements have also been linked to anxiety reduction.
Valerian fruit root is another popular herbal remedy for anxiety and stress relief. Valerian root studies are related to increased GABA levels in the brain, similar to passionflower, helping to induce relaxation and reduce anxiety symptoms. Learn more about valerian root for anxiety.
Ashwagandha is an adaptogenic herb — which are herbs believed to help manage stress in the body and restore balance after an extreme stress response is triggered. It’s used to help the body manage stress by balancing cortisol levels and supporting adrenal function. Studies have found that adults with chronic stress who use ashwagandha supplementation were able to reduce their anxiety scores significantly.
There is no comparative study on passionflower vs, ashwagandha for anxiety relief. However, both herbs might benefit people experiencing anxiety symptoms — you should talk to your doctor to determine which might suit you. If you want to know more about the benefits of ashwagandha, learn more about ashwagandha for anxiety.
Saint John’s Wort is an herbal supplement said to be used by some as a natural alternative to antidepressant medications. It’s thought to increase serotonin levels in the brain to promote happiness and well-being. Both passionflower and Saint John’s Wort might help to alleviate symptoms related to mood disorders like anxiety or depression. Comparing them is challenging since no significant bodies of research have looked at the benefits or risks of one compared to the other.
Finding treatments that can help alleviate your anxiety symptoms is crucial if you hope to deal with this condition. Natural remedies for anxiety might help. That said, you may find that it doesn’t work at all for you or that you need more than just passionflower for anxiety relief. It’s imperative that you seek to identify the cause of anxiety and learn coping tools to manage it.
Talkspace aims to help people cope with mental health conditions like anxiety. When you use Talkspace, you have a convenient, affordable, and accessible way to connect with licensed and experienced therapists. If you’re curious about how online therapy for anxiety works at Talkspace, reach out today.
Elsas S-M, Rossi DJ, Raber J, et al. Phytomedicine. 2010;17(12):940-949. doi:10.1016/j.phymed.2010.03.002. Accessed April 22, 2023.
Akhondzadeh S, Naghavi HR, Vazirian M, Shayeganpour A, Rashidi H, Khani M. Journal of Clinical Pharmacy and Therapeutics. 2001;26(5):363-367. doi:10.1046/j.1365-2710.2001.00367.x. Accessed April 22, 2023.
Movafegh A, Alizadeh R, Hajimohamadi F, Esfehani F, Nejatfar M. Anesthesia & Analgesia. 2008;106(6):1728-1732. doi:10.1213/ane.0b013e318172c3f9. Accessed April 22, 2023.
Chandrasekhar K, Kapoor J, Anishetty S. Indian Journal of Psychological Medicine. 2012;34(3):255-262. doi:10.4103/0253-7176.106022. Accessed April 22, 2023.
Elsas S-M, Rossi DJ, Raber J, et al. Phytomedicine. 2010;17(12):940-949. doi:10.1016/j.phymed.2010.03.002. Accessed April 22, 2023.
Bisma Anwar is the Team Lead for the Talkspace Council of Mental Health Experts. A major focus in her work has been anxiety management and helping her clients develop healthy coping skills, reduce stress and prevent burnout. She serves on the board of a non-profit organization based in NYC called The Heal Collective which promotes advocacy and awareness of mental health issues in BIPOC communities.