Ashwagandha for Anxiety: Does it Work?

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Anxiety Disorder
Read Time: 5 Minutes
Written by:Dr. Muhammad Munir, MD

Published On: January 23, 2024

Medically reviewed by: Bisma Anwar, MA, MSc, LMHC

Reviewed On: January 23, 2024

Updated On: July 1, 2024

Overview

Today, many people are looking for natural remedies for anxiety to relieve anxiety symptoms instead of or in addition to anxiety medication. In addition to therapy and prescription medications, supplements and herbs have found their place in treatment plans — but does ashwagandha help with anxiety? Some research suggests it can.

Ashwagandha — also referred to as Indian ginseng, Withania somnifera, or winter cherry— is an Indian herb from the root of the ashwagandha plant. Ashwagandha root extract has been used for thousands of years for medicinal purposes to treat various illnesses and overall well-being. The big question is, is ashwagandha good for anxiety — read on to explore the answer and the different benefits of Ashwagandha.

Does Ashwagandha Work for Anxiety?

Ashwagandha’s effectiveness as a natural remedy to reduce chronic stress and relieve anxiety has been suggested by multiple studies. In one randomized controlled study, participants who took a high concentration of ashwagandha root extract had significantly reduced stress levels compared to participants who received the placebo.

Another study saw similar results, finding that people with generalized anxiety disorder (GAD) saw improved outcomes and symptom relief after taking the ashwagandha for 6 weeks.

The science behind ashwagandha’s effects on anxiety

Ashwagandha supplements have various bioactive compounds that contribute to its anxiety relief properties. Though we’re not completely clear on the exact ways ashwagandha helps reduce anxiety, researchers do believe it involves multiple factors, including:

  • Adaptogenic properties: As an adaptogen (a substance that helps relieve and manage stress), ashwagandha might help the body adapt to anxiety.
  • GABA-mimetic effects: Research shows ashwagandha can mimic the effects of gamma-aminobutyric acid (GABA), a neurotransmitter that regulates anxiety and stress levels in the brain.
  • Cortisol reduction: In much of the research, a high cortisol level has been linked to increased stress and anxiety. Some studies have found that ashwagandha can reduce cortisol levels, which may have an anti-anxiety effect.

iconExpert Insight

“Some theories on mechanism of action are Ashwagandha is a GABA agonist, it enhances the production of GABA neurotransmitter in CNS. In addition, it enhances serotonin receptors in the brain. This blocks the stress signals and full anxiety response helping to stay calm”
Psychiatrist, MD, DFAPA Muhammad Munir

Active compounds in ashwagandha

There are some essential active compounds found in ashwagandha supplements, including:

  • Withanolides: These naturally occurring steroids have been found to exhibit anti-inflammatory, immunomodulatory, and neuroprotective properties.
  • Sitoindosides: Another steroid, sitoindosides have antioxidant properties thought to be anti-stress agents.
  • Alkaloids: Various alkaloids have been found in ashwagandha root extracts. Some alkaloids might have adaptogenic effects, which help the body manage anxiety and restore balance after encountering stressful events.

Impact on stress hormones

An ashwagandha supplement can help the body manage stress by altering physiological reactions, like reducing a person’s cortisol level. It also can impact neurochemicals involved in mood regulation, like serotonin and gamma-aminobutyric acid (GABA).

Does ashwagandha calm the mind?

A key benefit of ashwagandha and anxiety relief is the potential to calm the mind, which can naturally alleviate symptoms of anxiety. This calming effect can be attributed to multiple factors, including the herb’s influence on neurotransmitter balance and stress-hormone regulation.

Ashwagandha’s influence on neurotransmitter balance

As mentioned, an ashwagandha supplement has withanolides, which might positively impact brain function. These compounds can help regulate neurotransmitter activity like serotonin, dopamine, and GABA. Research has consistently shown that an imbalance in these neurotransmitters can lead to anxiety and depression.

How fast does ashwagandha work for anxiety?

It’s important to know that ashwagandha and anxiety reduction will not happen immediately. It can take several weeks before the full benefits are felt. For some people, ashwagandha benefits can even take months to take effect.

Factors influencing how long it takes ashwagandha to start working include individual tolerance and differences, other medications taken, dosage and form, and lifestyle.

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How to Use Ashwagandha for Anxiety

Ashwagandha can be used in multiple forms, including capsules, powders, or teas.

  • Capsules: Some people would rather take supplements in capsule form since it’s convenient and easy. You can find ashwagandha capsules at health food stores or from online retailers.
  • Powder: Ashwagandha powder is common and easy to find. Taking it in powder form allows you to control the amount you get. It can be mixed with water or milk or added to smoothies or recipes, like energy balls or muffins.
  • Tea: If you enjoy warm beverages before bedtime or during extreme moments of anxiety or stress, you can find pre-made ashwagandha tea blends. You can also brew your own tea by mixing a powder into hot liquid.

Possible Side Effects

You should know about potential side effects and interactions from any drug or supplement you take. Ashwagandha can cause individual reactions that vary, but some common side effects include:

  • Mild digestive issues: Some people experience mild upset stomach, diarrhea, or vomiting after they take ashwagandha. To minimize symptoms, start with a lower dose and gradually increase as your body adjusts.
  • Drowsiness: Due to its calming properties, ashwagandha can make some people drowsy. If you experience drowsiness as a side effect, avoid driving or operating heavy machinery when taking ashwagandha.
  • Allergic reaction: In rare cases, allergic reactions can occur after taking ashwagandha. Symptoms could include itching, rash, swelling of the face or throat, or difficulty breathing. If you experience any of these side effects, discontinue use immediately and contact your doctor.

Integrating Ashwagandha into Your Anxiety Management Routine

You can combine ashwagandha with your anxiety management treatment plan and other anxiety-reducing strategies for optimal results. However, make sure to talk to your doctor before starting supplements.

Combining ashwagandha with other treatments

Using ashwagandha with other anxiety-reducing techniques — like therapy for anxiety, self help techniques, or in addition to other medication — can be an effective form of treatment.

Psychotherapy and online counseling

Ashwagandha might be a helpful supplement to treat anxiety. However, it can be even more effective when combined with evidence-based therapies.

Cognitive behavioral therapy (CBT) is a widely used and effective therapy for anxiety. CBT works by helping you identify and change negative and unhealthy thoughts and behavior patterns that might contribute to your anxiety.

When you combine CBT or other therapeutic modalities with ashwagandha, you can experience more significant improvements in managing your anxiety symptoms.

Lifestyle changes and self-care

You should always consider fundamental lifestyle changes and practicing self-care activities when treating anxiety — meditation, yoga, journaling, and other self-help activities have been found very effective in treating anxiety.

Monitoring your progress and adjusting your approach

Anytime you integrate a supplement into your care routine, you should monitor how it affects you. This is true with ashwagandha, too. When you start using ashwagandha, track changes in your mood or anxiety levels over time. This will help you determine how effective it is in reducing anxiety. If your anxiety is not improving or worsening, you might want to talk to a healthcare professional about trying other vitamins for anxiety.

When to consult a professional

If you’re considering using ashwagandha for anxiety relief, it is vital to consult with your doctor. Discussing new supplements ensures they won’t interfere with any current medication regime. If you notice any worsening symptoms or concerning side effects during the treatment, immediately reach out to a mental health professional. Supplements like ashwagandha, which are not always FDA regulated, may vary in reliability; therefore, your medical professional or psychiatrist can guide you towards trusted brands and advise whether to continue its use, or recommend alternative treatments to manage your anxiety effectively.

The good news is anxiety is a very treatable condition. You don’t have to live with the impact it creates on your life, relationships, and mental well-being. Get connected with a therapist at Talkspace to find treatment for anxiety.

See References

Muhammad Munir

Dr. Muhammad Munir, MD, DFAPA, has over 20 years of clinical experience specializing in mood disorders, anxiety disorders, bipolar disorder, PTSD, panic disorder, and ADHD. Dr. Munir believes in “back to basics” the therapeutic alliance between the physician and patients. The hallmark of this alliance is the emphatic process whereby the patient is not only enabled, but educated and encouraged, to take an active role in their psychiatric care and wellbeing.

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