Updated On: May 16, 2024
Wellbutrin (bupropion) is an antidepressant medication in the norepinephrine-dopamine reuptake inhibitor (NDRI) class of drugs. NDRIs work by altering norepinephrine and dopamine levels in the brain to improve mood and stress response, among other things. Although most often prescribed for depressive disorder, Wellbutrin can also be used to treat anxiety symptoms. In fact, some studies suggest it might be as effective as the more traditionally used SSRIs when anxiety is comorbid with depression.
If you’re living with anxiety, and it’s impacting your life, relationships, and daily functioning, it’s time to seek help. Only a doctor or psychiatric provider can determine if anxiety medication might be beneficial for your symptoms, so don’t be afraid to reach out.
Learn more about the possibility of using Wellbutrin for anxiety, including how it can help, how long it takes to work, side effects you might experience, dosage, and other considerations.
Yes — for some people, Wellbutrin can be beneficial in relieving or reducing anxiety symptoms. As noted, it can be particularly effective for people who have depression and anxiety. For them, or for anyone who has difficulty remaining motivated as a result of their anxiety, certain medications, including Wellbutrin, might be helpful in reducing anxiety levels.
Recent research also suggests that using Wellbutrin for GAD may be effective when people with generalized anxiety disorder haven’t had success with more traditional anxiety medications, like selective serotonin reuptake inhibitors (SSRIs).
At one time, there was concern that Wellbutrin might potentially increase anxiety, but more recent research has all but debunked this. While anxiety is a listed side effect of Wellbutrin, certain studies show that it’s actually one of the rarest.
Get an evaluation and prescription online from a licensed psychiatric provider to improve your well-being.
How long it takes Wellbutrin to work when treating anxiety can depend from person to person. It can take weeks before symptoms improve when using Wellbutrin for depression, and when treating anxiety, a similar timeline might be expected.
According to some research, people taking Wellbutrin can experience improvements in energy, sleep, and appetite within 1 – 2 weeks.
Like any medication, Wellbutrin treatment can cause side effects. It’s important to be aware of them so you can talk to your healthcare provider if necessary — especially if any side effects become so uncomfortable that you want to discuss adjusting your treatment plan.
Most of the common Wellbutrin side effects are mild and often resolve as the body adjusts to the new antidepressant medication.
Common Wellbutrin side effects can include:
Some side effects can be more severe and should be discussed with your primary care doctor immediately:
Wellbutrin dosage for anxiety generally starts low and can be gradually increased over time. Unlike depression, there isn’t a straightforward or standard dose for anxiety treated with Wellbutrin.
Although doctors might prescribe a dose that ranges anywhere from 75 mg to 150 mg per day to start when treating depression, anxiety dosages will likely be much smaller. Adjustments can be made based on your response and tolerance.
Like any drug, it’s vital to follow a medical professional’s dosing instructions exactly as they’re given. Be sure to note and report any side effects if dosage recommendations change.
Before you take Wellbutrin for anxiety, you should discuss the following considerations with a medical professional. They can evaluate your specific symptoms and your medical and medication history. Because Wellbutrin is an antidepressant that’s used off-label for anxiety, it’s even more important to be aware of the following considerations.
Expert Insight
“Wellbutrin is a dual receptor medication that works for anxiety disorders. One should never stop the Wellbutrin cold turkey as that can cause withdrawal and possible seizures.”Psychiatrist, MD, DFAPA Muhammad Munir
Wellbutrin isn’t the only option you have to treat symptoms of anxiety. There is no one-size-fits-all when it comes to anxiety treatment. A drug that might work well for one person may not work at all for someone else. Fortunately, you have dozens of options when it comes to treating anxiety via therapy and or other drugs.
Many types of therapy can effectively treat anxiety symptoms. Types of therapy that are known for their efficacy in treating anxiety include:
Anti-anxiety medications are available and can be very effective in treating symptoms of anxiety. Popular drugs used to treat anxiety include:
*Note: Benzos are generally only prescribed for short-term use and have a risk of tolerance and dependency.
Expert Insight
“Wellbutrin is an excellent choice for anxiety disorders without the side effects of SSRIs (mainly sexual side effects) limiting treatment. It is also used in combination with other medications for augmentation and relieving the anxiety symptoms.”Psychiatrist, MD, DFAPA Muhammad Munir
Talkspace offers convenient, affordable, and readily accessible online anxiety treatment. It allows you to connect with an online psychiatrist to discuss your medication and treatment options for individualized anxiety treatment and medication management. If you’re wondering about taking Wellbutrin for anxiety, Talkspace has you covered.
Contact Talkspace today to learn how to get anxiety medication, like Wellbutrin, online.
Poliacoff Z, Belanger HG, Winsberg M. Journal of Clinical Psychopharmacology. 2023;43(2):152-156. doi:10.1097/jcp.0000000000001658. Accessed March 26, 2024.
Melaragno AJ. FOCUS. 2021;19(2):145-160. doi:10.1176/appi.focus.20200048. Accessed March 26, 2024.
Patel K, Allen S, Haque MN, Angelescu I, Baumeister D, Tracy DK. Therapeutic Advances in Psychopharmacology. 2016;6(2):99-144. doi:10.1177/2045125316629071. Accessed March 26, 2024.
Drugs.com. August 22, 2022. Accessed March 26, 2024.
Dr. Muhammad Munir, MD, DFAPA, has over 20 years of clinical experience specializing in mood disorders, anxiety disorders, bipolar disorder, PTSD, panic disorder, and ADHD. Dr. Munir believes in “back to basics” the therapeutic alliance between the physician and patients. The hallmark of this alliance is the emphatic process whereby the patient is not only enabled, but educated and encouraged, to take an active role in their psychiatric care and wellbeing.