Gabapentin for Anxiety: All You Need to Know

Anxiety Disorder
Read Time: 5 Minutes
Written by:Dr. Muhammad Munir, MD

Published On: May 16, 2024

Medically reviewed by: Olga Molina, D.S.W., LCSW

Reviewed On: May 16, 2024

Updated On: May 16, 2024

Overview

Anxiety disorders are the most common type of mental health condition today. They affect millions of people and can significantly impact relationships, self-image, and quality of life in general. It’s estimated that more than 300 million people worldwide live with an anxiety disorder that causes them excessive worry, fear, and constant nervousness. Fortunately, help is available, and anxiety is highly treatable with therapy and anxiety medication like Gabapentin.

Gabapentin is a drug that was initially developed and FDA-approved to treat epilepsy and chronic pain. However, today, it’s commonly used off-label to treat some types of anxiety disorders effectively.

If you or someone you love lives with moderate or severe anxiety and is looking for a treatment option, keep reading to explore the link between Gabapentin and anxiety

Does Gabapentin Help with Anxiety?

Some research suggests that Gabapentin can effectively alleviate anxiety symptoms in some people. That said, the efficacy of this prescription medication can vary from person to person. 

It’s important to know that Gabapentin is not FDA-approved specifically for the treatment of anxiety. Still, it has been used off-label — that is, not initially intended for anxiety medication, but may help — to treat several types of anxiety disorders.

Gabapentin is thought to work by affecting neurotransmitters in the brain, like gamma-aminobutyric acid (GABA). GABA helps regulate anxiety and stress responses in the brain, so increasing levels can cause a calming effect, reducing feelings of anxiety and promoting relaxation.

While more research is warranted, some studies show certain types of anxiety and depression can be helped with Gabapentin, including:

  • Social anxiety  
  • Seasonal affective disorder (SAD)
  • Specific phobias, like public speaking 
  • Perioperative anxiety

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How Fast Does Gabapentin Work for Anxiety?

Like any drug, the timeline for Gabapentin to start working and reducing symptoms of anxiety varies. It can take several weeks or longer to see the full benefits. 

One study found that breast cancer patients taking Gabapentin for anxiety felt significant improvement and relief after four weeks. Some research notes that the effects of Gabapentin are often evident within one week, but it can take up to a month before complete relief is felt. 

As with any prescription medication, it’s important to be patient if Gabapentin is used for anxiety and isn’t the quick fix you were looking for. Take Gabapentin exactly as directed. If you’re concerned about its efficacy or side effects, be sure to talk to your doctor before discontinuing use.

Side Effects to Expect When Taking Gabapentin for Anxiety

All drugs have a risk of potential side effects — Gabapentin is no different. Though it can offer relief for anxiety symptoms in some people, it’s essential to be aware of possible side effects you might experience when taking Gabapentin. 

Having a comprehensive understanding of any adverse effect you might feel, in addition to anxiety relief, will help you and your doctor make informed decisions about whether or not Gabapentin is the best option for you.

Potential side effects of Gabapentin for anxiety can include:

  • Dizziness: One of the most common side effects reported with Gabapentin use. 
  • Drowsiness or sedation: Sedative effects can impact cognitive function and alertness, so be careful when driving or using machinery until you know how Gabapentin will affect you. 
  • Fatigue: Many people experience increased fatigue as an adverse effect when taking Gabapentin.
  • Coordination problems: This drug can cause balance and coordination issues and lead to difficulty with fine motor skills. 
  • Changes in mood: Gabapentin might cause a change in mood or behavior in some people — look for increased irritability, depression, or agitation when starting this drug. 
  • Gastrointestinal disturbances: In some people, Gabapentin can cause gastrointestinal issues like nausea, vomiting, diarrhea, or constipation. 
  • Weight gain: Weight gain is a possible common side effect when taking Gabapentin.
  • Withdrawal symptoms: Never stop taking Gabapentin suddenly — doing so can lead to Gabapentin withdrawal symptoms like increased anxiety, sweating, nausea, insomnia, or seizures.

Not everyone will experience all (or any) of these side effects. Many people tolerate Gabapentin well and have no issues at all or only experience minimal side effects. However, if you feel that the side effects you’re having outweigh the benefits you’re getting, make sure you let your doctor know. They may consider changing your dosage or trying a different drug to treat your moderate to severe anxiety.

Gabapentin Dosage for Anxiety

If your doctor prescribes Gabapentin for anxiety, make sure you take it exactly as directed. Determining the correct dosage will depend on individual factors like the severity of your symptoms, your medical history, and how you respond to treatment.

The common dosage for Gabapentin can range between 300 mg and 3,600 mg and up to 4,800 mg per day, depending on the type of anxiety. For example, one study assessed anxiety in breast cancer patients and found that 300 mg significantly improved their symptoms. Another study looked at doses up to 3,600 mg to treat social phobia.

Considerations for Taking Gabapentin for Anxiety

Before taking any drug to treat anxiety, it’s essential to understand the considerations and precautions associated with it. To determine if Gabapentin is the right choice for managing your anxiety, discuss the following with your healthcare provider or psychiatrist.

Important considerations related to Gabapentin used for anxiety include:

  • Medical history
  • Other medications you’re taking — especially other sedating drugs
  • Other conditions you currently have
  • Your age and weight
  • If you’re pregnant or breastfeeding, or you plan to become pregnant or start breastfeeding in the near future
  • Knowing what side effects to monitor for
  • Understanding that dizziness and sedation are common

iconExpert Insight

“Gabapentin is an excellent choice for anxiety disorders with little accompanying physical and pain symptoms. It is a calming medication with multiple uses, which are dose-dependent. Be careful with the start of the medication, as sedation and dizziness can be challenging at times. Don’t combine with other sedating medications”
Psychiatrist, MD, DFAPA Muhammad Munir

Find Relief with Online Anxiety Treatment

Anxiety can be challenging to live with. It can make daily functioning, personal and professional relationships, and a sense of self-worth difficult. If you’re experiencing symptoms of anxiety and are looking for help, Talkspace can be the solution you’ve been seeking. 

Talkspace is an affordable, convenient online platform that connects you with an online psychiatrist who’s experienced in treating anxiety disorders and understands what types of therapy and medication might be beneficial.

Reach out to Talkspace to work with a psychiatrist and start discussing your options — including Gabapentin for anxiety — and get a personalized anxiety treatment that will change your life.

Learn how to get anxiety medication, like Gabapentin, online with Talkspace.

See References

Muhammad Munir

Dr. Muhammad Munir, MD, DFAPA, has over 20 years of clinical experience specializing in mood disorders, anxiety disorders, bipolar disorder, PTSD, panic disorder, and ADHD. Dr. Munir believes in “back to basics” the therapeutic alliance between the physician and patients. The hallmark of this alliance is the emphatic process whereby the patient is not only enabled, but educated and encouraged, to take an active role in their psychiatric care and wellbeing.

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