Lexapro & Weight Gain: What to Know

Updated 3/20/24

Lexapro (escitalopram) is a common psychiatrist-prescribed medication that’s been proven effective in helping to manage symptoms related to depression and anxiety. It’s not without side effects, though. Research suggests that some people gain weight on a Lexapro prescription.  

If you’re considering taking Lexapro or are already on it and have noticed weight change, you might be wondering why Lexapro weight gain occurs. Once you understand more about this potential side effect, you can make informed decisions about whether or not Lexapro is right for you. 

Keep reading to learn more about Lexapro and weight gain. We’re covering how much weight some people gain, why weight change might happen, how to avoid it, and more. 

Why Does Lexapro Cause Weight Gain?

Several factors can contribute to the relationship between Lexapro and weight gain. For example, some medications are known to cause an increase in appetite, changes in metabolism, or fluid retention. In addition, some people find it challenging to maintain an active lifestyle when feeling low or anxious — which can also contribute to weight gain over time if left unchecked.

The exact reason Lexapro might cause weight gain isn’t fully understood yet. However, many experts believe that changes in metabolism or appetite could play a role in causing this particular side effect. Other possible explanations include increased cravings for carbohydrates or increased fat storage due to decreased physical activity caused by low energy levels associated with depression or anxiety medications like Lexapro.

Research identifies multiple possible explanations for why someone might gain weight on Lexapro. Some of them include the following: 

Sedentary lifestyle

Some people who aren’t active or don’t work out might be more prone to gaining weight when on depression or anxiety medication like Lexapro. 

Serotonin levels changing

One theory about Lexapro and weight gain is that increased serotonin levels can lead to changes in appetite or metabolism, resulting in unwanted weight gain. 

Increased cravings

Another possibility is that an SSRI antidepressant like Lexapro can increase cravings for certain types of food, including carbohydrates or sweets. 

Smoking

Some people with a history of smoking might gain weight after starting prescription antidepressant treatment. 

As always it’s important to talk to your doctor before you smoke or use any substance alongside Lexapro. Lexapro and alcohol are not recommended together so be sure you always talk to your doctor about potential interactions.

Increased appetite 

Finally, some people simply eat more when feeling better emotionally due to improved moods from antidepressants like Lexapro. Depression and anxiety can cause a decreased appetite so a reduction of those symptoms can improve someone’s appetite, potentially resulting in weight changes. 

Does Lexapro Weight Gain Go Away?

It’s not uncommon for people to experience weight gain while taking Lexapro. The good news is that this side effect often might go away once the body adjusts to the drug and your metabolism returns to normal.

How long does weight gain from Lexapro last?

The duration of Lexapro weight gain varies from person to person. Some people experience it immediately after starting the medication. Others, though, might only notice changes once they have taken it for several weeks or months. It might be the case that the longer you take Lexapro, the more likely it is that you’ll experience some weight gain.

How to Avoid Gaining Weight on Lexapro

If you want to try and avoid the potential side effect of gaining too much weight while on Lexapro, there are steps you can take. Here are some tips to help prevent weight gain when taking Lexapro:

• Eat healthy foods: Following a healthy diet, including foods such as fruits and vegetables, lean proteins, whole grains, and low-fat dairy products can help keep your body fueled with the nutrients it needs without adding extra calories or fat. Avoid processed foods high in sugar and saturated fats which can lead to weight gain.
• Exercise regularly: Regular exercise helps maintain a healthy weight. Working out also releases endorphins that can improve mood and reduce stress levels (both of which have been linked to overeating or unhealthy eating habits). Aim for at least 30 minutes of moderate physical activity each day. Try things like walking, jogging, yoga, or cycling.
• Monitor your weight: Keeping track of your weight regularly will help you identify any changes quickly so that you can make adjustments if needed. Some people find it helpful to weigh themselves once a week at the same time, wearing similar clothing each time for accuracy.

“Learning to manage weight gain while on Lexapro will be helpful in ensuring the benefits of the medication are aiding the symptoms of depression. Weight gain can cause additional health-related risks but also more symptoms of depression heavily related to the weight gain. Ensuring proactive changes to diet and exercise, employing healthy coping skills, and talking to the psychiatrists and therapists will be important in managing those side effects.”

– Talkspace therapist Minkyung Chung, MS, LMHC

If you notice significant weight gain or changes in your appetite while taking Lexapro, talk to your doctor immediately. They may suggest adjusting the dosage or switching medications if necessary. Additionally, they can advise on how best to manage any other side effects associated with this drug, including unwanted weight gain.

By making lifestyle changes and focusing on weight management while taking Lexapro, you can avoid gaining weight. 

Some natural supplements are also available that have been shown effective at reducing symptoms associated with depression. Some are effective without causing significant Lexapro side effects like increased appetite or cravings. You can ask your doctor about these options as well.

Talk to Your Doctor About Lexapro Side Effects

While Lexapro can be effective in treating your mental health condition, there are side effects — like the possibility of weight gain — to be aware of before starting the medication.  

Understanding the potential Lexapro side effects can help determine if the drug might be a good option as part of your treatment plan. Your doctor will ensure you understand what might occur and how to best manage side effects like increased body weight. Be sure to also talk to your doctor about other medical advice regarding Lexapro, such as using Lexapro while pregnant.

Lexapro weight gain can be a common side effect, but it doesn’t impact everyone who takes this medication. Multiple studies conclude that certain antidepressant medication like Lexapro can result in weight gain. However, it varies from person to person depending on individual factors such as age, lifestyle habits, diet, and activity level.

Understanding the nuances of Lexapro and its potential side effects, such as weight gain, is crucial for anyone considering this medication as part of their treatment plan. While lifestyle adjustments can help mitigate some risks, it’s vital to have professional guidance tailored to your unique health profile and concerns.

Talkspace recognizes the importance of accessible, comprehensive mental health support, especially when navigating the complexities of medication like Lexapro. Our online psychiatry services provide a convenient way to connect with licensed psychiatrists from the comfort of your home. Whether you’re experiencing side effects, have concerns about Lexapro and weight gain, or are seeking alternatives, our team is here to support you. Our psychiatrists can offer personalized advice, adjust prescriptions as necessary, and explore other treatment options that align better with your health goals and lifestyle.